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APExBIO社 試薬(弊社は、正規輸入代理店です。)
(An Apoptosis; アポトーシス研究用試薬)
*掲載品はすべて、試験研究用途として用いるものです。

1.
Apoptosis Inducers (アポトーシス誘導物質)

Bendamustine HCl
Catalog No.
A1984
CAS No.
3543-75-7
解説:
An alkalating agent associated with DNA damage with IC50 of 50μm (50μmのIC50におけるDNAの損傷と関連したアルキル化剤)
容量:
5mg, 10mg
Brassinolide
Catalog No.
A3265
CAS No.
72962-43-7
解説:
Plant growth regulator (植物成長調整物質、茎伸長と細胞分裂促進 )
容量:
10nM (in 1mL DMSO), 5mg, 10mg
Epibrassinolide
Catalog No.
B4782
CAS No.
78821-43-9
解説:
Steroidal plant growth stimulant
(ブラシノステロイド(ステロイドから派生した植物成長調節物質の一群)の生物活性化合物です。非-腫瘍細胞成長に影響を及ぼすことのないいろいろなガン細胞の潜在的アポトーシスの誘因)
容量:
5mg, 25mg
TW-37
Catalog No.
A4234
CAS No.
877877-35-5
解説:
Bcl-2 Inhibitor (Bcl-2 阻害剤、ペプチド抑制剤)
TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.
容量:
10mg, 25mg, 50mg, 100mg
7BIO
Catalog No.
C5685
CAS No.
916440-85-2
解説:
caspase independent nonapoptotic cell death inducer
容量:
10mg, 50mg
ML-291
Catalog No.
C5358
CAS No.
1523437-16-2
解説:
Apoptosis Inducer (アポトーシス誘導物質)
容量:
5mg, 10mg, 25mg
Psoralidin
Catalog No.
C4962
CAS No.
18642-23-4
解説:
Apoptosis Inducer (アポトーシス誘導物質)
容量:
5mg, 10mg, 25mg, 100mg
Destruxin B
Catalog No.
C4423
CAS No.
2503-26-6
解説:
Apoptosis Inducer (アポトーシス誘導物質)
容量:
1mg
15-acetoxy Scirpenol
Catalog No.
C4698
CAS No.
2623-22-5
解説:
mycotoxin that induce apoptotic cell deth  (アポトーシス誘導物質; 細胞死誘発)
容量:
1mg, 5mg
MPI-0441138
Catalog No.
C3296
CAS No.
827030-33-1
解説:
inducer of apoptosis growth inhibition  (アポトーシス誘導物質; 成長抑制誘因)
容量:
5mg, 10mg, 25mg
CFM4
Catalog No.
B7760
CAS No.
331458-02-7
解説:
Interferes with CARP-1 binding to APC-2
容量:
10mg, 50mg
NSC687852 (b-AP15)
Catalog No.
A4453
CAS No.
1009817-63-3
解説:
19S regulatory particle inhibitor
容量:
10mg, 50mg, 200mg
BAM7
Catalog No.
A3218
CAS No.
331244-89-4
解説:
BAX activator, direct and selective (直接かつ選択的な BAX活性剤)
容量:
10mg, 50mg
Matrine (マトリン)
Catalog No.
A3583
CAS No.
519-02-8
解説:
Alkaloid found in Sophora plant (抗癌作用を持つアルカロイド)
容量:
100mg, 200mg, 500mg
R1530
Catalog No.
A3746
CAS No.
882531-87-5
解説:
Antiangiogenesis, mitosis-angiogenesis inhibitor (MAI)(血管新生阻害剤)
容量:
10mg, 50mg
SMIP004
Catalog No.
A3846
CAS No.
143360-00-3
解説:
Apoptosis Inducer (アポトーシス誘導物質)
容量:
5mg, 10mg, 25mg, 50mg
Trabectedin (トラベクテジン)
Catalog No.
A3886
CAS No.
114899-77-3
解説:
Antitumour agent (抗癌剤)
Trabectedin (Ecteinascidin-743 or ET-743) is a novel antitumour agent of marine origin with potent antitumour activity both in vitro and in vivo.
容量:
1mg
Raltegravir potsssium salt
Catalog No.
B4760
CAS No.
871038-72-1
解説:
HIV integrase inhibitor  (HIVインテグラーゼ阻害剤)
Raltegravir potassium salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.
容量:
5mg, 10mg, 50mg, 100mg
PM00104
Catalog No.
B1228
CAS No.
解説:
Potent antimyeloma agent (抗骨髄腫剤)
Zalypsis(PM00104) is an alkaloid analog to certain natural marine compound. Zalyps is a potent antimyeloma agent with IC50 values from picomolar to low nanomolar ranges.
容量:
1mg
Meisoindigo
Catalog No.
B3255
CAS No.
97207-47-1
解説:
Apoptosis Inducer; Potential agent for AML (アポトーシス誘導物質)
Meisoindigo is a potential agent for acute myeloid leukemia.
容量:
5mg, 10mg, 50mg, 100mg
2,3-DCPE hydrochloride
Catalog No.
A4447
CAS No.
418788-90-6
解説:
Bcl-XL protein expression downregulator
Selectively induces apoptosis and downregulates Bcl-XL protein expression in various human cancer cells versus normal cells in vitro. IC50 values are 0.89 and 12.6 μM for LoVo human colon cancer cell line and normal human fibroblasts respectively. Induces p21 expression and S-phase arrest in cancer cells via ERK-mediated pathways.
容量:
10mg, 50mg
C75
Catalog No.
A4449
CAS No.
191282-48-1
解説:
Fatty acid synthase (FAS) inhibitor (脂肪酸シンターゼ阻害剤)
Synthetic inhibitor of fatty acid synthase (FAS); inhibits fatty acid synthesis in vitro and in vivo. Displays anorectic effects. Induces apoptosis in MCF-7 xenografts and exhibits anti-tumor activity.
容量:
10mg, 50mg
CHM1
Catalog No.
A4450
CAS No.
154554-41-3
解説:
Tubulin polymerization inhibitor (チューブリン重合阻害剤)
Inducer of apoptosis; displays potent antitumor ability in human hepatocellular carcinoma. Inhibits tubulin polymerization in vitro and in vivo. Causes cell cycle arrest at G2/M phase by activation of Cdc2 kinase activity. Induces translocation of apoptosis inducing factor (AIF) from the mitochondria to nucleus. Also exhibits vascular targeting activity through upregulation of p53 and induction of death receptor (DR5)-mediated apoptosis in HUVEC cells.
容量:
10mg, 50mg
Deguelin(デグエリン)
Catalog No.
A4451
CAS No.
522-17-8
解説:
Anticancer and antiviral agent (抗癌剤・抗ウイルス剤)
Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC50 values are 11 and 6.9 nM respectively). Inhibits PI 3-kinase and reduces pAkt levels in pre-malignant and malignant human bronchial epithelial cells. Active in vivo.
容量:
10mg
Oncrasin 1
Catalog No.
A4454
CAS No.
75629-57-1
解説:
Proapoptotic agent (アポトーシス促進剤)
Oncrasin 1 is a small molecule antitumor agent with IC50 value of 4.81 μM.
容量:
10mg, 50mg
Plumbagin(プルンバギン)
Catalog No.
A4456
CAS No.
481-42-5
解説:
Anticancer agent (抗癌剤)
Anticancer agent. Induces G2/M cell cycle arrest and apoptosis in A549 cells through JNK-dependent p53 Ser15 phosphorylation; inhibits A549 and MDA-MD-231 tumour xenograft growth in nude mice. Promotes autophagic cell death in MDA-MB-231 and MCF-7 cells and inhibits Akt/mTOR signaling. Induces intracellular ROS generation in a PI 5-kinase-dependent manner.
容量:
5mg, 25mg

日本国内での価格、納期等は一丸貿易株式会社にお問い合わせください。

一丸貿易株式会社

Eメール:
info@ichimarutrading.co.jp

2.
Bcl-2 Family(Bcl-2 ファミリータンパク質)

WEHI-539
Catalog No.
A3935
CAS No.
1431866-33-9
解説:
Bcl-xL inhibitor, potent and selective (Bcl-xL 阻害剤)
WEHI-539 is a small-molecule inhibitor of BCLXLwith an IC50 value of 1.1 nM.
容量:
5mg, 10mg, 50mg
BH3I-1
Catalog No.
B6094
CAS No.
300817-68-9
解説:
Bcl-2 or Bcl-xL inhibitor (Bcl-2阻害剤, Bcl-xL 阻害剤)
容量:
2mg, 5mg, 10mg, 25mg, 50mg
S63845
Product No.
A8737
CAS No.
1799633-27-4
解説:
MCL1 inhibitor(MCL1 阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
A-1210477
Catalog No.
B6011
CAS No.
1668553-26-1
解説:
MCL1 inhibitor(MCL1 阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 25mg
BDA-366
Catalog No.
B5978
CAS No.
NA
解説:
Selective antagonist of BCL2 BH4 domain
容量:
5mg, 25mg
Radotinib (IY-5511)(ラドチニブ)
Catalog No.
B5846
CAS No.
926037-48-1
解説:
Bcr-Abl tyrosine kinase inhibitor (Bcr-Abl チロシンキナーゼ阻害剤)
容量:
10mM(in 1mL DMSO), 5mg, 10mg, 25mg, 50mg
(+)-Apogossypol
Catalog No.
B4902
CAS No.
66389-74-0
解説:
inhibitor of Bcl-2 family proteins (Bcl-2 ファミリータンパクの阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg
Pyridoclax
Catalog No.
B4901
CAS No.
NA
解説:
xxMc-1 inhibitor (Mc-1 阻害剤)xx
容量:
5mg, 10mg, 50mg, 100mg
UMI-77
Catalog No.
B4881
CAS No.
518303-20-3
解説:
Mc-1 inhibitor, novel (Mc-1 阻害剤)
容量:
5mg, 25mg
TW-37
Catalog No.
A4234
CAS No.
877877-35-5
解説:
Bcl-2 inhibitor, inhibits Bcl-2, Bcl-XL and Mcl (Bcl-2 阻害剤)
容量:
10mM (in 1mL DMSO), 10mg, 25mg, 50mg, 100mg
ABT-263 (Navitoclax)
Catalog No.
A3007
CAS No.
923564-51-6
解説:
Potent Bcl-2 family inhibitor, inhibits Bcl-2, Bcl-xL, and Bcl-w
(Bcl-2 ファミリー阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 50mg, 100mg
ABT-737
Catalog No.
A8193
CAS No.
852808-04-9
解説:
Bcl-2 inhibitor(Bcl-2 阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 50mg, 100mg, 500mg
ABT-199
Catalog No.
A8194
CAS No.
1257044-40-8
解説:
Bcl-2 inhibitor, potent and selective(Bcl-2 阻害剤)
容量:
10mM (in 1mL DMSO), 1mg, 5mg, 50mg
Obatoclax mesylate (GX15-070)
Catalog No.
A4194
CAS No.
803712-79-0
解説:
Potent Bcl-2 inhibitor(Bcl-2 阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 50mg
HA14-1
Catalog No.
A8168
CAS No.
65673-63-4
解説:
Bcl-2 inhibitor, potent and cell-permeable (Bcl-2 阻害剤)
容量:
10mM (in 1mL DMSO), 20mg, 50mg, 200mg
Marinopyrrole A
Catalog No.
B1080
CAS No.
1227962-62-0
解説:
Selective Bcl-2 inhibitor (選択的Bcl-2 阻害剤)
容量:
5mg, 10mg, 50mg, 100mg
Bax inhibitor peptide V5
Catalog No.
A4461
CAS No.
579492-81-2
解説:
Bax inhibitor (Bax 阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 100mg
Bax inhibitor peptide P5
Catalog No.
A4460
CAS No.
579492-83-4
解説:
Bax inhibitor (Bax 阻害剤)
容量:
5mg, 10mg, 100mg
BAM7
Catalog No.
A3218
CAS No.
331244-89-4
解説:
BAX activator, direct and selective (BAX活性剤)
容量:
10mg, 50mg
Sabutoclax
Catalog No.
A4199
CAS No.
1228108-65-3
解説:
pan-Bcl-2 inhibitor (pan-Bcl-2 阻害剤)
容量:
5mg, 50mg
Apogossypolone (ApoG2)
Catalog No.
A4200
CAS No.
886578-07-0
解説:
Bcl-2 inhibitor, nonpeptidic small molecule(Bcl-2 阻害剤)
容量:
5mg, 25mg
BM-1074
Catalog No.
A4198
CAS No.
1391108-10-3
解説:
Bcl-2/Bcl-xL inhibitor, potent and selective(Bcl-2/Bcl-xL 阻害剤)
容量:
10mg, 25mg, 50mg, 100mg
Bax channel blocker
Catalog No.
A4459
CAS No.
335165-68-9
解説:
Inhibitor of Bax-medicated mitochondrial cytochrome c release
容量:
10mg, 50mg
Bax Inhibitor peptide, negative control
Catalog No.
A4462
CAS No.
1315378-74-5
解説:
Peptide inhibitor Bax translocation to mitochondria
容量:
1mg
BIM, Biotinylated
Catalog No.
A4463
CAS No.
NA
解説:
Bim peptide fragment with a biotin moiety attached
容量:
1mg
iMAC2
Catalog No.
A4464
CAS No.
335166-36-4
解説:
MAC inhibitor(MAC 阻害剤)
容量:
10mg, 50mg
MIM1
Catalog No.
A4465
CAS No.
NA
解説:
Mcl-1 inhibitor(Mcl-1 阻害剤)
容量:
10mg, 50mg
Muristerone A
Catalog No.
A4466
CAS No.
38778-30-2
解説:
TRAIL- and hFasL-induced apoptosis inhibitor
容量:
1mg
2,3-DCPE hydrochloride
Catalog No.
A4447
CAS No.
418788-90-6
解説:
Bcl-XL protein expression downregulator
容量:
10mg, 50mg
Gossypol
Catalog No.
N2135
CAS No.
303-45-7
解説:
PAF inhibitor; anti-fertility and anit-cancer (PAF阻害剤)
容量:
10mM (in 1mL DMSO), 50mg, 100mg, 200mg
AT-101
Catalog No.
A3196
CAS No.
90141-22-3
解説:
BH3-mimetic, gossypol enantiomer
容量:
10mg, 50mg
Mcl1-IN-1
Catalog No.
B4691
CAS No.
713492-66-1
解説:
Myeloid cell factor 1 inhibitor
容量:
5mg, 10mg, 50mg, 100mg

日本国内での価格、納期等は一丸貿易株式会社にお問い合わせください。

一丸貿易株式会社

Eメール:
info@ichimarutrading.co.jp

3.
MDM2

Nutlin-3b
Catalog No.
A2005
CAS No.
675576-97-3
解説:
MDM2/p53 inhibitor (MDM2/p53 阻害剤)
容量:
5mg, 10mg, 50mg
JNJ-26854165 (Serdemetan)
Catalog No.
A4204
CAS No.
881202-45-5
解説:
P53 activator, blocking Mdm2-p53 interaction (P53 活性剤)
容量:
10mM (in 1mL DMSO), 5mg, 25mg, 100mg
SP 141
Catalog No.
C4120
CAS No.
1253491-42-7
解説:
Mdm2 inhibitor (Mdm2 阻害剤)
容量:
5mg, 10mg, 50mg
(±)-Nutlin-3
Catalog No.
B6058
CAS No.
548472-68-0
解説:
MDM2 antagonist, potent and selective(MDM2拮抗剤)
容量:
5mg, 10mg, 50mg
MI-773 (SAR405838)
Catalog No.
B4984
CAS No.
1303607-60-4
解説:
orally available MDM2 antagonist(MDM2拮抗剤)
容量:
5mg, 10mg, 50mg
Pifithrin-β
Catalog No.
B4813
CAS No.
60477-34-1
解説:
potent p53 inhibitor(p53阻害剤)
容量:
5mg, 10mg, 50mg
RG7112
Catalog No.
A3762
CAS No.
939981-39-2
解説:
MDM2 inhibitor, first clinical(MDM2阻害剤)
容量:
10mM (in 1mL DMSO), 10mg, 100mg
RITA (NSC 652287)
Catalog No.
A4202
CAS No.
213261-59-7
解説:
Mdm2-p53 intaeraction and p53 ubiquitination blocking
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 50mg
RG7388
Catalog No.
A3763
CAS No.
1229705-06-9
解説:
MDM2 antagonist, oral, selective(MDM2拮抗剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 50mg
p53 and MDM2 proteins-interaction-inhibitor chiral
Catalog No.
A3693
CAS No.
939981-37-0
解説:
p53 and MDM2 proteins-interaction-inhibitor
容量:
10mg, 100mg
p53 and MDM2 proteins-interaction-inhibitor racemic
Catalog No.
A3694
CAS No.
939983-14-9
解説:
p53 and MDM2 proteins-interaction-inhibitor
容量:
10mg, 100mg
YH239-EE
Catalog No.
B4756
CAS No.
1364488-67-4
解説:
p53-MDM2 antagonist, potent(p53-MDM2拮抗剤)
容量:
10mg, 50mg
NSC 207895 (XI-006)
Catalog No.
A4209
CAS No.
58131-57-0
解説:
MDMX inhibitor, anti-cancer agent(MDMX阻害剤、抗癌剤)
容量:
5mg, 10mg, 50mg, 200mg

日本国内での価格、納期等は一丸貿易株式会社にお問い合わせください。

一丸貿易株式会社

Eメール:
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4.
PC-PLC

U-73343
Catalog No.
B9013
CAS No.
142878-12-4
解説:
negative control of U-73122 for PLC inhibition
容量:
10mg
U-73122
Catalog No.
B3422
CAS No.
112648-68-7
解説:
inhibitor of phospholipase C, phospholipase A2, and 5-LO (5-lipoxygenase)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg
SPK-601
Catalog No.
A3833
CAS No.
1096687-52-3
解説:
Potent PC-PLC inhibitor, antimicrobial agent (PC-PLC抑制剤、抗菌剤)
容量:
10mg, 50mg
RHC 80267
Catalog No.
B9005
CAS No.
83654-05-1
解説:
diacylglycerol lipase inhibitor (ジアシルグリセロール阻害剤)
容量:
10mg, 25mg, 50mg

日本国内での価格、納期等は一丸貿易株式会社にお問い合わせください。

一丸貿易株式会社

Eメール:
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5.
Caspase

Z-VAD-FMK
Catalog No.
A1902
CAS No.
187389-52-2
解説:
Cell-permeable, irreversible pan-caspase inhibitor(細胞透過性非可逆性パン―カスパーゼ阻害剤)
容量:
10mM (in 1mL DMSO), 1mg, 5mg, 10mg, 25mg
Se-Aspirin
Catalog No.
C5667
CAS No.
1850293-95-6
解説:
nonsteroidal anti-inflammatory drug(非ステロイド抗炎症剤)
容量:
5mg, 10mg, 50mg
Z-Asp-CH2-DCB
Catalog No.
C4981
CAS No.
153088-73-4
解説:
caspase inhibitor(カスパーゼ阻害剤)
容量:
5mg, 10mg, 25mg, 50mg
Ac-DEVD-CMK
Catalog No.
C5528
CAS No.
285570-60-7
解説:
cell-permeable, and irreversible caspase inhibitor(細胞透過性で不可逆的カスパーゼ阻害剤)
容量:
5mg, 10mg, 25mg, 50mg
Ac-DEVD-AFC
Catalog No.
C5524
CAS No.
201608-14-2
解説:
fluorogenic substrate for activated caspase-3 (活性されたカスパーゼ-3用の蛍光発生基質)
容量:
1mg, 5mg, 10mg
NS3694
Catalog No.
C4468
CAS No.
426834-38-0
解説:
inhibits apoptosome formation and caspase activation
容量:
5mg, 10mg, 25mg, 50mg
Z-YVAD-FMK
Catalog No.
A8955
CAS No.
N/A
解説:
Caspase-1 inhibitor(カスパーゼ-1阻害剤)
容量:
10nM (in 1mL DMSO), 1mg, 5mg
Caspase-3/7 Inhibitor I
Catalog No.
A1925
CAS No.
220509-74-0
解説:
Caspase-3/7 inhibitor(カスパーゼ-3/7 阻害剤)
容量:
10mM (in 1ml DMSO), 1mg, 5mg, 10mg, 25mg
Q-VD-OPh hydrate
Catalog No.
A1901
CAS No.
1135695-98-5
解説:
cell-permeable, and irreversible pan-caspase inhibitor(細胞透過性で不可逆的パン-カスパーゼ阻害剤)
容量:
10mM (in 1ml DMSO), 1mg, 5mg, 10mg, 25mg
VX-765
Catalog No.
A8238
CAS No.
273404-37-8
解説:
Caspase-1 inhibitor, potent and selective(カスパーゼ-1阻害剤)
容量:
10mM (in 1ml DMSO), 5mg, 10mg, 50mg, 100mg
Z-VEID-FMK
Catalog No.
A1923
CAS No.
N/A
解説:
Caspase-6 inhibitor(カスパーゼ-6阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
Z-VDVAD-FMK
Catalog No.
A1922
CAS No.
N/A
解説:
Caspase-2 inhibitor (カスパーゼ-2阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
Z-DQMD-FMK
Catalog No.
A1921
CAS No.
N/A
解説:
Caspase-3 inhibitor, cell-permeable(カスパーゼ-3 阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
Z-DEVD-FMK
Catalog No.
A1920
CAS No.
210344-95-9
解説:
Caspase-3 inhibitor (カスパーゼ-3 阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
Q-VD(OMe)-OPh
Catalog No.
A8165
CAS No.
N/A
解説:
Pan-caspase inhibitor(パン-カスパーゼ阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
PAC-1
Catalog No.
A8177
CAS No.
315183-21-2
解説:
Caspase-3 activator(カスパーゼ-3 活性剤)
容量:
10mM (in 1mL DMSO), 10mg, 25mg, 50mg, 100mg, 250mg
Z-LEHD-FMK
Catalog No.
B3233
CAS No.
210345-04-3
解説:
Irreversible Caspase-9 inhibitor(非可逆的カスパーゼ-9 阻害剤)
容量:
1mg, 5mg
Z-IETD-FMK
Catalog No.
B3232
CAS No.
210345-04-3
解説:
Caspase-8 inhibitor(カスパーゼ-8 阻害剤)
容量:
10mM (in 1mL DMSO), 1mg, 5mg
Z-WEHD-FMK
Catalog No.
A1924
CAS No.
210345-00-9
解説:
Caspase 5 inhibitor,potent,cell-permeable and irreversible(カスパーゼ-5 阻害剤)
容量:
1mg, 5mg, 10mg, 25mg
Boc-D-FMK
Catalog No.
A1904
CAS No.
187389-53-3, 634911-80-1
解説:
Pan-caspase inhibitor(パン-カスパーゼ 阻害剤)
容量:
10mM (in 1mL DMSO), 1mg, 5mg, 10mg, 25mg
Ac-IEPD-AFC
Catalog No.
A4418
CAS No.
1135417-31-0
解説:
Recognition motif for serine protease granzyme B
容量:
5mg
Ac-LEHD-AFC
Catalog No.
A4419
CAS No.
210345-03-2
解説:
Fluorogenic caspase substrate
容量:
5mg
Gambogic Acid
Catalog No.
A3424
CAS No.
2752-65-0
解説:
Caspase activator and apoptosis inducer
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg
Apoptosis Activator 2
Catalog No.
A4016
CAS No.
79183-19-0
解説:
Indoledione caspase activator, cell-permeable
容量:
10mg, 25mg, 50mg, 100mg
Z-FA-FMK
Catalog No.
A8170
CAS No.
79183-19-0
解説:
Cysteine proteases inhibitor(システイン プロテアーゼ 阻害剤)
容量:
10mM (in 1mL DMSO), 1mg, 5mg, 10mg, 25mg
AZ 10417808
Catalog No.
A4416
CAS No.
331645-84-2
解説:
Caspase-3 inhibitor,selective non-peptide(カスパーゼ-3 阻害剤)
容量:
10mg, 50mg
Ivachtin
Catalog No.
A4417
CAS No.
745046-84-8
解説:
Caspase-3 inhibitor(カスパーゼ-3 阻害剤)
容量:
1mg, 10mg
PETCM
Catalog No.
A4420
CAS No.
10129-56-3
解説:
Caspase-3 activator(カスパーゼ-3 活性剤)
容量:
50mg
Emricasan
Catalog No.
B4618
CAS No.
254750-02-2
解説:
potent irreversible pan-caspase inhibitor(非可逆的パン-カスパーゼ阻害剤)
容量:
1mg

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6.
IAP(アポトーシス阻害因子)

Triptolide
Catalog No.
A3891
CAS No.
38748-32-2
解説:
IL-2/MMP-3/MMP7/MMP19 inhibitor
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 1g
AT-406 (SM-406)
Catalog No.
A3019
CAS No.
1071992-99-8
解説:
IAP inhibitor(IAP阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 25mg
SM-164
Catalog No.
A8815
CAS No.
957135-43-2
解説:
Anticancer agent (抗癌剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 200mg
Embelin
Cataolog No.
A8235
CAS No.
957135-43-2
解説:
XIAP inhibitor,cell-permeable(XIAP 阻害剤)
容量:
10mM (in 1mL DMSO), 10mg, 50mg
YM155
Catalog No.
A4221
CAS No.
781661-94-7
解説:
Survivin suppressant,apoptosis inhibitor
(サーバイビン抑制剤、アポトーシス阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 100mg
Birinapant (TL32711)
Catalog No.
A4219
CAS No.
1260251-31-7
解説:
Potent XIAP/cIAP1 antagonist(XIAP/cIAP1 拮抗剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 50mg
GDC-0152
Catalog No.
A4224
CAS No.
873652-48-3
解説:
IAP antagonist,potent amd samll-molecule (IAP拮抗剤)
容量:
10mM (in 1mL DMSO), 10mg, 50mg, 100mg
LCL161
Catalog No.
A3541
CAS No.
1005342-46-0
解説:
Antagonist of IAPs inhibitor
容量:
10mM (in 1mL DMSO), 5mg, 25mg, 50mg, 100mg
BV6
Catalog No.
B4653
CAS No.
1001600-56-1
解説:
Selective inhibitor of IAP proteins
容量:
10mM (in 1mL DMSO), 5mg, 25mg, 100mg

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7.
p-53

Pifithrin-α (PFTα)
Catalog No.
A4206
CAS No.
63208-82-2
解説:
p53 Inhibitor (p53 阻害剤)
容量:
10mM (in 1mL DMSO), 5mg, 25mg, 50mg
Nutlin-3
Catalog No.
A4228
CAS No.
890090-75-2
解説:
MDM2 antagonist,inhibits MDM2-p53 interaction(MDM2拮抗剤)
容量:
10mM (in 1mL DMSO), 5mg, 10mg, 25mg, 100mg
p-nitro-Cyclic Pifithrin-α
Catalog No.
C5104
CAS No.
60477-38-5
解説:
inactivator of p53 (p53 の不活性化剤)
容量:
5mg, 10mg, 25mg
GN25
Catalog No.
C4840
CAS No.
1227401-27-5
解説:
p53-Snail binding inhibitor
容量:
10mg, 25mg, 50mg
COTI-2
Catalog No.
C4483
CAS No.
1039455-84-9
解説:
activates mutant forms of p53
容量:
5mg, 10mg, 25mg
p-nitro-Pifithrin-α
Catalog No.
C3846
CAS No.
389850-21-9
解説:
inactivator of p53
容量:
10mg, 25mg
CBL0137 (hydrochlorie)
Catalog No.
C3192
CAS No.
1197397-89-9
解説:
curaxin that activates p53 and inhibits NF-kB
容量:
1mg, 5mg, 10mg, 25mg
CBL0137
Catalog No.
C3171
CAS No.
1197996-80-7
解説:
curaxin that activates p53 and inhibits NF-kB
容量:
1mg, 5mg, 10mg
NSC348884
Catalog No.
B6190
CAS No.
81624-55-7
解説:
nucleophosmin inhibitor
容量:
5mg, 25mg, 100mg
NSC59984
Catalog No.
B6045
CAS No.
803647-40-7
解説:
Restores the p53 signaling pathway
容量:
5mg, 25mg
ONC201
Catalog No.
A8724
CAS No.
1616632-77-9
解説:
activates p53-independent apoptosis
容量:
5mg, 10mg, 50mg, 100mg
Tenovin-3
Catalog No.
A8567
CAS No.
1011301-27-1
解説:
p53 activator(p53 活性剤)
容量:
10mM(in 1mL DMSO), 1mg, 5mg, 10mg, 25mg
SJ172550
Catalog No.
A4486
CAS No.
431979-47-4
解説:
MDMX inhibitor(MDMX 阻害剤)
容量:
10mg, 50mg
Nutlin-3a chiral
Catalog No.
A3671
CAS No.
675576-98-4
解説:
MDM2 inhibitor, antiproliferative and antiproapoptotic(MDM2阻害剤)
容量:
10mM (in 1mL DMSO), 10mg, 50mg, 200mg
PRIMA-1
Catalog No.
A4483
CAS No.
5608-24-2
解説:
BAX inhibitor(BAX阻害剤)
容量:
10mM(in 1mL DMSO), 5mg, 10mg, 50mg
Tenovin-1
Catalog No.
A4203
CAS No.
380315-80-0
解説:
SIRT2 inhibitor, activates p53(SIRT2 阻害剤)
容量:
10mM(in 1mL DMSO), 25mg, 50mg, 100mg
Cyclic Pifithrin-α hydrochloride (別名: Pifithrin-β)
Catalog No.
A4477
CAS No.
511296-88-1
解説:
p53 inhibitor(p53 阻害剤)
容量:
5mg, 10mg, 25mg, 50mg
RG7112
Catalog No.
A3762
CAS No.
939981-39-2
解説:
MDM2 inhibitor, first clinical(MDM2阻害剤)
容量:
10mM (in 1mL DMSO), 10mg, 100mg
tumor protein p53 binding protein fragment [Homo sapiens]/[Mus musculus]
Catalog No.
A1094
CAS No.
NA
解説:
p53 binding protein fragment(p53 結合タンパク質)
容量:
5mg, 10mg, 25mg
CP 31398 dihydrochloride
Catalog No.
A4476
CAS No.
1217195-61-3
解説:
p53 stabilizer(p53 安定剤)
容量:
10mg, 50mg
Plumbagin
Catalog No.
A4456
CAS No.
481-42-5
解説:
Anticancer agent(抗癌剤)
容量:
10mM (in 1ml DMSO), 5mg, 25mg
AMG232
Catalog No.
A8804
CAS No.
1352066-68-2
解説:
p53-MDM2 inhibitor, novel(p53-MDM2 阻害剤)
容量:
5mg, 10mg, 50mg, 100mg
HLI 373
Catalog No.
A4478
CAS No.
502137-98-6
解説:
Hdm2 ubiquitin ligase (E3) inhibitor
容量:
10mg, 50mg
Piperlongumine
Catalog No.
A4455
CAS No.
20069-09-4
解説:
Inducer of cell-death
容量:
10mM(in 1mL DMSO), 10mg, 50mg
NSC 319726
Catalog No.
A4208
CAS No.
71555-25-4
解説:
Reactivator of mutant p53
容量:
10mM (in 1mL DMSO), 5mg, 25mg
MIRA-1
Catalog No.
A4479
CAS No.
72835-26-8
解説:
Restorer of wild-type p53 conformation/cellular function
容量:
10mg, 50mg
NSC 146109 hydrochloride
Catalog No.
A4480
CAS No.
59474-01-0
解説:
Antitumor agent, p53-dependent transcription activator
容量:
10mg, 50mg
PhiKan 083
Catalog No.
A4481
CAS No.
880813-36-5
解説:
p53 stabilizer(p53 安定剤)
容量:
10mg, 50mg
RETRA hydrochlorie
Catalog No.
A4485
CAS No.
1036069-26-7
解説:
Antitumor agent(抗腫瘍薬)
容量:
10mg, 50mg
WR 1065
Catalog No.
A4487
CAS No.
14653-77-1
解説:
p53/p21waf-1/MDM2 activator(p53/p21waf-1/MDM2 活性剤)
容量:
10mg, 50mg
NVP-CGM097
Catalog No.
B4677
CAS No.
1313363-54-0
解説:
potent and selective MDM2 inhibitor(MDM2阻害剤)
容量:
2mg, 5mg, 10mg, 50mg, 100mg

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8.
TNF-α(腫瘍壊死因子-α)

Necrostatin-1
Catalog No.
A4213
CAS No.
4311-88-0
解説:
RIP1 inhibitor(RIP1 阻害剤)
容量:
10mM(in 1mL DMSO), 10mg, 100mg
Pomalidomide (CC-4047) (ポマリドミド)
Catalog No.
A4212
CAS No.
19171-19-8
解説:
Immunomodulator, antumor/anti-angiogenic
(免疫調整物質、血管新生阻害剤)
容量:
10mM(in 1mL DMSO), 5mg, 10mg, 50mg, 200mg
Lenalidomide (CC-5013)(レナリドミド)
Catalog No.
A4211
CAS No.
191732-72-6
解説:
Antineoplastic agent, inhibits angiogenesis
(抗悪性腫瘍薬、血管形成阻害)
容量:
10mM(in 1mL DMSO), 50mg, 100mg, 250mg, 500mg
Maslinic Acid
Catalog No.
C4832
CAS No.
4373-41-5
解説:
Inhibitor of NO, H2O2, IL-6 and THF-α
容量:
5mg, 10mg, 25mg
R-7050
Catalog No.
C3129
CAS No.
303997-35-5
解説:
TNF-α receptor signaling antagonist, cell-permeable
容量:
5mg, 10mg, 25mg
GSK481
Catalog No.
B6194
CAS No.
1622849-58-4
解説:
RIP1(Receptor Interacting Protein Kinase 1) inhibitor
(RIP1 阻害剤)
容量:
2mg, 5mg, 25mg
CPI-1189
Catalog No.
B6109
CAS No.
183619-38-7
解説:
necrosis factor (TNF) alpha inhibitor
容量:
5mg, 25mg
Lenalidomide hydrochloride
Catalog No.
A3547
CAS No.
1243329-97-6
解説:
TNF-α secretion inhibitor(TNF-α分泌阻害剤)
容量:
50mg, 100mg, 250mg, 500mg
Necrostatin 2
Catalog No.
A3652
CAS No.
852391-19-6
解説:
In vitro necroptosis inhibitor (試験管内ネクロプトーシス阻害剤)
容量:
5mg, 10mg, 25mg, 50mg
Lenalidomide hemihydrate
Catalog No.
B1188
CAS No.
847871-99-2
解説:
TNF-α secretion inhibitor(TNF-α分泌阻害剤)
容量:
50mg, 100mg, 250mg, 500mg
Necrostatin 2 racemate
Catalog No.
A3960
CAS No.
852391-15-2
解説:
In vitro necroptosis inhibitor (試験管内ネクロプトーシス阻害剤)
容量:
5mg, 10mg, 25mg, 50mg
Necrostatin 2 S enantiomer
Catalog No.
A3961
CAS No.
852391-20-9
解説:
In vitro necroptosis inhibitor (試験管内ネクロプトーシス阻害剤)
容量:
5mg, 10mg, 25mg, 50mg
Roquinimex
Catalog No.
B3921
CAS No.
84088-42-6
解説:
quinline derivative immunostimulant
容量:
10mg, 50mg

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9.
PKD

CRT 0066101
Catalog No.
A8679
CAS No.
NA
解説:
PKD inhibitor (PKD 阻害剤)
容量:
10mM(in 1mL DMSO), 10mg, 100mg
CID 755673
Catalog No.
A8678
CAS No.
521937-07-5
解説:
PKD inhibitor (PKD 阻害剤)
容量:
10mM(in 1mL DMSO), 5mg, 10mg, 50mg
CID 2011756
Catalog No.
A8223
CAS No.
638156-11-3
解説:
PKD inhibitor(PKD 阻害剤)
容量:
10mM(in 1mL DMSO), 5mg, 10mg, 50mg
kb NB 142-70
Catalog No.
A3524
CAS No.
1233533-04-4
解説:
inhibitor of protein kinase D, selective (プロテインキナーゼD選択的阻害剤)
容量:
10mM(in 1mL DMSO), 10mg, 50mg
CRT5
Catalog No.
C4165
CAS No.
1034297-58-9
解説:
PKD1, PKD2 and PKD3 inhibitor(PKD 阻害剤)
容量:
5mg, 10mg, 25mg

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